Tofatin -XR (Tofacitinib) 11mg

Tofatin -XR (Tofacitinib) 11mg

Tofatin-XR 11mg contains Tofacitinib, a Janus kinase (JAK) inhibitor used to manage autoimmune conditions such as rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. It works by reducing inflammation and regulating overactive immune responses.

Field Details
Original Brand Xeljanz
Generic Brand Tofatin-XR
Generic Name Tofacitinib 11mg
Pack Size 30 Extended-Release Tablets
Use / Indications Rheumatoid Arthritis, Psoriatic Arthritis, Ulcerative Colitis
Manufacturer Everest Pharmaceuticals Ltd. (Produced in Bangladesh)
Status Prescription Only Medicine

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Quantity

Introduction to Xeljanz (Tofacitinib) 11mg 

Tofatin-XR (Tofacitinib) 11mg is a prescription medicine used to treat autoimmune diseases such as rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. It belongs to a class of drugs called Janus kinase (JAK) inhibitors, which help regulate the immune system to reduce inflammation and prevent joint and tissue damage.

Tofatin-XR (Tofacitinib) 11mg is classified under Prescription Medicines, Immunomodulatory Drugs, JAK Inhibitors, and Oral Anti-Inflammatory Therapies. It contains Tofacitinib, which works by blocking specific enzymes involved in the inflammatory process, thereby reducing overactive immune responses.

Generic versions such as Tofatin-XR 11mg may also be available, providing similar therapeutic effects when prescribed by a qualified healthcare professional.

What Is Xeljanz (Tofacitinib)? 

Xeljanz is the original brand name for Tofacitinib, an oral JAK inhibitor used to manage autoimmune disorders.

Tofacitinib belongs to a class of medicines known as Janus kinase (JAK) inhibitors. These medicines block enzymes that contribute to inflammation, helping reduce immune system overactivity and tissue damage.

Generic formulations such as Tofatin-XR 11mg contain the same active ingredient and may be used depending on physician recommendation and regional availability.

Drug Class and Mechanism of Action 

Tofacitinib is classified as a JAK inhibitor with immunomodulatory and anti-inflammatory properties.

How Tofacitinib Works 

It works in several ways:

  • Inhibits Janus kinase (JAK) enzymes involved in inflammatory signaling
  • Reduces overactive immune responses
  • Helps prevent joint, skin, and gut tissue damage

Through these mechanisms, Tofacitinib helps manage symptoms and slow disease progression in autoimmune conditions.

How Xeljanz Works in the Body 

Tofacitinib modulates intracellular signaling in immune cells, reducing cytokine production and inflammation.

Key Actions of Tofacitinib 

  • Decreases joint swelling, pain, and stiffness
  • Reduces skin inflammation in psoriatic arthritis
  • Controls intestinal inflammation in ulcerative colitis

Some generic versions such as Tofatin-XR deliver the same active compound, allowing similar immune-modulating therapy when prescribed appropriately.

Medical Uses of Xeljanz (Tofacitinib) 11mg 

Tofacitinib 11mg is prescribed for several autoimmune conditions.

Tofacitinib for Rheumatoid Arthritis 

Helps reduce joint inflammation, pain, and stiffness in adults with moderate to severe rheumatoid arthritis.

Potential Benefits 

  • Improves joint function and mobility
  • Reduces swelling and tenderness
  • Slows disease progression

Tofacitinib for Psoriatic Arthritis and Ulcerative Colitis 

Used to control skin, joint, and intestinal inflammation.

Treatment Benefits 

  • Reduces disease flare-ups and symptoms
  • Supports improved quality of life
  • Provides a convenient oral therapy option

Who Can Take Tofatin-XR 11mg? 

Because Tofacitinib is a potent immunomodulatory drug, treatment should always be supervised by a qualified healthcare provider.

Eligibility Criteria 

Patients may be prescribed Tofacitinib if they:

  • Have moderate to severe rheumatoid arthritis, psoriatic arthritis, or ulcerative colitis
  • Can undergo regular monitoring for infections and blood counts
  • Are not at high risk for serious infections or malignancies

Certain generic options such as Tofatin-XR may also be considered depending on availability and physician decision.

Who Should Avoid Xeljanz (Tofacitinib) 11mg 

Tofacitinib should NOT be used by:

  • Patients with active serious infections
  • Individuals with known hypersensitivity to Tofacitinib
  • Pregnant or breastfeeding women unless advised by a doctor
  • Patients with history of blood clots, malignancy, or liver impairment without supervision

Xeljanz (Tofacitinib) 11mg Dosage and Administration 

Standard Dosage Guidelines 

Typical dosage recommendations include:

  • Tofatin-XR 11mg taken orally once daily
  • Can be taken with or without food
  • Extended-release formulation allows once-daily dosing

Dosage Adjustments 

Doctors may adjust the dose depending on:

  • Kidney or liver function
  • Side effect profile
  • Concomitant medications

Side Effects of Tofacitinib 11mg 

Like all immunomodulatory medicines, Tofacitinib may cause side effects.

Common Side Effects 

  • Headache
  • Upper respiratory infections
  • Diarrhea or nausea
  • Mild changes in blood counts

Serious Side Effects 

Serious Infections: Tuberculosis, bacterial, or viral infections
Blood Clots: Risk of deep vein thrombosis or pulmonary embolism
Malignancy Risk: Rare increased risk with long-term therapy

Patients should report any unusual symptoms to their doctor immediately.

Storage:
Store below 25°C in a cool, dry place, protected from moisture and sunlight. Keep tablets in original packaging and out of reach of children.

Frequently Asked Questions (FAQs) 

1. What is Tofacitinib 11mg used for? 

It is used to treat autoimmune diseases such as rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis.

2. Can Tofacitinib increase infection risk? 

Yes. Because it suppresses the immune system, patients are at higher risk of bacterial, viral, and fungal infections.

3. Can Tofatin-XR 11mg be taken with food? 

Yes. It can be taken with or without food.

4. Is Tofatin-XR 11mg the same as Xeljanz? 

Tofatin-XR 11mg contains Tofacitinib, the same active ingredient found in Xeljanz. Generic versions is available. for more info. contact on WhatsApp: https://wa.me/8801742433764

5. Do I need a prescription to buy Tofatin-XR (Tofacitinib) 11mg? 

Yes. Tofatin-XR 11mg is a prescription-only medicine and should be used under the supervision of a qualified healthcare professional.

Medical Disclaimer 

Disclaimer:
The information provided on this page is for educational and informational purposes only and should not be considered medical advice. Tofacitinib is a prescription-only immunomodulatory drug and must be used strictly under the supervision of a qualified healthcare professional. Always consult your physician before starting, stopping, or changing any medication.

 

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